Speaker

Adam Abate

Professor

Department of Bioengineering and Therapeutic Sciences
Schools of Medicine and Pharmacy
University of California, San Francisco

Abstract

Many fundamental questions in biology hinge on understanding the interactions of millions of single cells. In my lab, we develop technologies to study large populations of single cells in detail. In this talk, I will outline our methods for sorting cells based on genomic and transcriptomic markers, as well as performing multi-omics analyses that enable the simultaneous characterization of genomic, transcriptomic, and proteomic signatures. Additionally, I will discuss how we are adapting these techniques to integrate genomics with other single-cell measurement approaches, including imaging, mass spectrometry, and atomic force microscopy. Lastly, I will describe the application of these techniques in infectious disease, oncology, and structural biology research.